Didier Letourneur Selected Research

fucoidan

10/2021	Fucoidan-functionalized polysaccharide submicroparticles loaded with alteplase for efficient targeted thrombolytic therapy.
12/2019	Pharmaceutical Development and Safety Evaluation of a GMP-Grade Fucoidan for Molecular Diagnosis of Cardiovascular Diseases.
1/2019	Functionalized polymer microbubbles as new molecular ultrasound contrast agent to target P-selectin in thrombus.
1/2018	Amino-Fucoidan as a Vector for rtPA-Induced Fibrinolysis in Experimental Thrombotic Events.
1/2018	Thrombolytic therapy based on fucoidan-functionalized polymer nanoparticles targeting P-selectin.
2/2017	Development of Polymer Microcapsules Functionalized with Fucoidan to Target P-Selectin Overexpressed in Cardiovascular Diseases.
1/2015	Ultrasmall superparamagnetic iron oxide nanoparticles coated with fucoidan for molecular MRI of intraluminal thrombus.
9/2014	Purification of a low molecular weight fucoidan for SPECT molecular imaging of myocardial infarction.
1/2014	Abdominal aortic aneurysms targeted by functionalized polysaccharide microparticles: a new tool for SPECT imaging.
12/2011	Therapeutic potential of fucoidan in myocardial ischemia.

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Didier Letourneur Research Topics

Disease

11	Thrombosis (Thrombus) 10/2021 - 09/2011
6	Atherosclerosis 01/2021 - 07/2007
6	Inflammation (Inflammations) 10/2019 - 08/2003
6	Hyperplasia 01/2019 - 05/2002
5	Neoplasms (Cancer) 11/2021 - 12/2013
5	Cardiovascular Diseases (Cardiovascular Disease) 12/2019 - 11/2006
5	Abdominal Aortic Aneurysm 02/2017 - 01/2008
4	Rupture 01/2020 - 01/2009
4	Atherosclerotic Plaque (Atheroma) 01/2020 - 01/2009
4	Myocardial Ischemia (Ischemic Heart Diseases) 12/2019 - 09/2011
4	Aneurysm (Aneurysms) 08/2014 - 11/2006
3	Ischemia 06/2019 - 04/2003
3	Wounds and Injuries (Trauma) 02/2015 - 09/2010
2	Ischemic Stroke 10/2021 - 12/2018
2	Hypoxia (Hypoxemia) 12/2018 - 03/2016
2	Coronary Artery Disease (Coronary Atherosclerosis) 09/2017 - 01/2009
2	Infections 02/2015 - 03/2011
2	Myocardial Infarction 09/2014 - 01/2012
2	Neointima 11/2006 - 01/2006
1	Metabolic Diseases (Metabolic Disease) 11/2021
1	Cerebral Infarction 10/2021
1	Stroke (Strokes) 01/2021
1	Bone Resorption 10/2020
1	Genomic Instability 09/2020
1	Insulin Resistance 07/2020
1	Hyperglycemia 07/2020
1	Suppuration 07/2019
1	Intracranial Hemorrhages (Intracranial Hemorrhage) 12/2018
1	Chronic Disease (Chronic Diseases) 01/2017
1	Hypersensitivity (Allergy) 03/2016
1	Acute Coronary Syndrome 09/2014
1	Vascular Diseases (Vascular Disease) 01/2014

Drug/Important Bio-Agent (IBA)

15	fucoidanIBA 10/2021 - 10/2002
11	Polysaccharides (Glycans)IBA 12/2019 - 10/2002
8	P-SelectinIBA 10/2021 - 09/2011
7	Contrast MediaIBA 01/2019 - 07/2007
4	LipidsIBA 01/2020 - 04/2009
4	Apolipoproteins E (ApoE)IBA 01/2020 - 03/2009
3	Biological ProductsIBA 11/2021 - 12/2006
3	AntioxidantsIBA 01/2020 - 01/2017
3	PolymersIBA 01/2019 - 02/2017
3	CollagenIBA 12/2018 - 11/2006
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2016 - 12/2011
3	Matrix Metalloproteinases (MMPs)IBA 09/2015 - 01/2009
3	Pancreatic Elastase (Elastase)IBA 01/2015 - 10/2010
2	Biocompatible Materials (Biomaterials)IBA 10/2021 - 08/2003
2	Tissue Plasminogen Activator (Alteplase)FDA Link 10/2021 - 12/2018
2	Insulin (Novolin)FDA Link 01/2021 - 07/2020
2	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2020 - 01/2020
2	Pharmaceutical PreparationsIBA 12/2019 - 04/2015
2	Fibronectins (Fibronectin)IBA 07/2019 - 12/2013
2	Bucrylate (Bucrilate)IBA 01/2019 - 01/2018
2	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 03/2016 - 04/2003
2	ferumoxtran-10 (ultrasmall superparamagnetic iron oxide)IBA 01/2015 - 12/2013
2	Tyrosine (L-Tyrosine)FDA Link 05/2011 - 11/2009
2	Matrix Metalloproteinase 2 (Gelatinase A)IBA 01/2011 - 01/2006
2	gadolinium 1,4,7,10- tetraazacyclododecane- N,N',N'',N'''- tetraacetateIBA 10/2010 - 03/2009
2	Dextrans (Dextran)FDA Link 09/2010 - 05/2002
2	Heparin (Liquaemin)FDA LinkGeneric 12/2006 - 08/2003
2	Phenobarbital (Luminal)FDA Link 11/2006 - 10/2002
1	Nucleic AcidsIBA 01/2021
1	Dental Implants (Dental Implant)IBA 10/2020
1	NAD (NADH)IBA 09/2020
1	EnzymesIBA 09/2020
1	SirtuinsIBA 09/2020
1	Radioisotopes (Radionuclides)IBA 12/2019
1	FucoseIBA 12/2019
1	CytokinesIBA 10/2019
1	CobaltIBA 10/2019
1	Polyurethanes (Polyurethane)IBA 10/2019
1	Thromboplastin (Tissue Factor)IBA 10/2019
1	tetrahydrofuranIBA 07/2019
1	Immunoglobulin G (IgG)IBA 07/2019
1	Proteins (Proteins, Gene)FDA Link 07/2019
1	astaxanthine (astaxanthin)IBA 06/2019
1	Thrombin FDA Link 01/2019
1	polybutyl methacrylate (PBMA)IBA 01/2019
1	lysyllysine (Lys-Lys)IBA 01/2018
1	FibrinIBA 09/2017
1	Capsules (Microcapsules)IBA 02/2017
1	Carotenoids (Carotene)IBA 01/2017
1	Leukotriene B4 Receptors (Leukotriene B4 Receptor)IBA 09/2015
1	Leukotriene B4IBA 09/2015
1	Interleukin-6 (Interleukin 6)IBA 09/2015
1	Photosensitizing Agents (Photosensitizers)IBA 04/2015
1	Silicon Dioxide (Silica)FDA LinkGeneric 06/2014
1	Cell Adhesion MoleculesIBA 01/2014
1	Technetium (Technetium 99m)IBA 01/2014
1	aspartic acid glycine arginineIBA 12/2013

Therapy/Procedure

5	Stents 01/2019 - 05/2002
3	Percutaneous Coronary Intervention 09/2017 - 01/2009
2	Intravenous Administration 12/2018 - 03/2016
1	Drug Therapy (Chemotherapy) 01/2020
1	Microbubbles 01/2019
1	Contraindications 12/2018
1	Thrombolytic Therapy 12/2018
1	Intravenous Injections 02/2017
1	Therapeutics 02/2017
1	Surgical Amputation (Amputations) 02/2015
1	Injections 01/2014